منابع مشابه
Gene Delivery to Mesenchymal Stem Cells
There is increasing trend in using recombinant stem cells as novel therapeutic candidates in different diseases. These studies encompass different applications from targeted homing of Mesenchymal Stromal (stem) Cells (MSC), to arming them with different cytokines. Resistance to transfection or transduction methods had urged researchers to look for better gene delivery alternates and optimizing ...
متن کاملHuman wild-type superoxide dismutase 1 gene delivery to rat bone marrow stromal cells: its importance and potential future trends
Objective(s): Human superoxide dismutase 1 (SOD1) is the cytosolic form of this enzyme it detoxifies superoxide anions and attenuates their toxicities and concomitant detrimental effects on the cells. It is believed that the amount of these enzymes present in the oxidative stress-induced diseases is crucial for preventing disease progression. Transfection of rat bone marrow stromal cells (BMSCs...
متن کاملP61: Non-Viral Human ProGDNF Gene Delivery to Rat Bone Marrow Stromal Cells under Ex Vivo Conditions
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملCorrigendum: Enhanced bone morphogenic protein adenoviral gene delivery to bone marrow stromal cells using magnetic nanoparticle
OBJECTIVES This study investigated the question of whether adenoviral magnetofection can be a suitable method for increasing the efficacy of gene delivery into bone marrow stromal cell (BMSC) and for generation of a high level of bone morphogenic protein (BMP) secretion at a minimized viral titer. MATERIALS AND METHODS Primary BMSCs were isolated from C57BL6 mice and transduced with adenovira...
متن کاملBiomaterials to gene delivery.
It has been over 40 years since I started biomaterials research. This article is a short summary of past research in my laboratory.
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ژورنال
عنوان ژورنال: Advanced Drug Delivery Reviews
سال: 2012
ISSN: 0169-409X
DOI: 10.1016/j.addr.2012.03.013